Defining the cellular logic of breast cancer

Breast cancer is not a single disease, and its ability to spread makes it especially difficult to treat. In our lab, we study how healthy breast cells grow, specialize, and interact with their environment—and how cancer cells hijack and repurpose those same developmental programs to invade new tissues and resist therapy.

By combining powerful tools like 3D organoid cultures, advanced imaging, single-cell analysis, and in vivo models, we explore how tumors evolve, how different cell types within a tumor cooperate, and what allows cancer cells to survive and grow in distant organs. We are especially focused on the molecular signals and cellular behaviors that enable metastasis, with the goal of identifying weak points that could be targeted with new therapies.